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Transpl Infect Dis ; 22(6): e13364, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-592352

ABSTRACT

Solid organ transplant recipients are considered at high risk for COVID-19 infection due to chronic immune suppression; little data currently exists on the manifestations and outcomes of COVID-19 infection in lung transplant recipients. Here we report 8 cases of COVID-19 identified in patients with a history of lung transplant. We describe the clinical course of disease as well as preexisting characteristics of these patients.


Subject(s)
COVID-19/physiopathology , Cross Infection/physiopathology , Immunosuppressive Agents/therapeutic use , Lung Transplantation , Adenosine Monophosphate/analogs & derivatives , Adenosine Monophosphate/therapeutic use , Adult , Aged , Alanine/analogs & derivatives , Alanine/therapeutic use , Antibodies, Monoclonal, Humanized/therapeutic use , Antiviral Agents/therapeutic use , COVID-19/diagnostic imaging , COVID-19/immunology , COVID-19/therapy , Cough/physiopathology , Cross Infection/diagnostic imaging , Cross Infection/immunology , Cross Infection/therapy , Cystic Fibrosis/surgery , Dyspnea/physiopathology , Female , Fever/physiopathology , Gastrointestinal Diseases/physiopathology , Glucocorticoids/therapeutic use , Graft Rejection/prevention & control , Humans , Idiopathic Pulmonary Fibrosis/surgery , Immunoglobulins, Intravenous/therapeutic use , Immunologic Factors/therapeutic use , Interleukin 1 Receptor Antagonist Protein/therapeutic use , Lung/diagnostic imaging , Male , Methylprednisolone/therapeutic use , Middle Aged , Pancreatitis, Acute Necrotizing , Pulmonary Disease, Chronic Obstructive/surgery , Pulse Therapy, Drug , SARS-CoV-2 , Sepsis , Severity of Illness Index , Tomography, X-Ray Computed
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